This issue of the ECDC Communicable Disease Threats Report (CDTR) covers the period 27 February – 5 March 2023 and includes updates on COVID-19, group A streptococcal infection, influenza and influenza A(H5N1) , Middle East respiratory syndrome coronavirus (MERS-CoV), Mpox, poliomyelitis, Marburg virus disease and the Earthquakes in Türkiye, Syria.