This issue of the ECDC Communicable Disease Threats Report (CDTR) covers the period 28 September – 4 October 2024 and includes updates on Marburg virus disease, Mpox, avian influenza A(H5N1) human cases, an overview of respiratory virus epidemiology in the EU/EEA, West Nile virus, dengue, SARS-CoV-2, MERS-CoV, and chikungunya.