This issue of the ECDC Communicable Disease Threats Report (CDTR) covers the period 12-18 October 2024 and includes updates on cVDPV2 in wastewater in Spain, cVDPV3 in environmental samples in French Guiana, avian influenza, Marburg virus disease, mpox, Wst Nile virus, dengue, poliomyelitis, and an overview of respiratory virus epidemiology in the EU/EEA.